A research study conducted by Brigham researchers has uncovered the way in which genetic alterations in specific brain cell types may play a role in the inflammation observed in Alzheimer’s disease. Microglia, immune-regulating cells in the brain, are known to be involved in the development of Alzh

According to this study, reduction in the activity of the INPP5D gene in microglia (immune regulating cells in the brain) leads to increased neuroinflammation, potentially contributing to the progression of Alzheimer’s disease, paving the way for targeted treatments.

https://www.nature.com/articles/s41467-023-42819-w (open access)