SELinux provides a strong security measure that can make an SELinux-enabled operating system a type of “fortress”: the so-called “confined users” [1] [2] [3], which add security and isolation capabilities that are in several respects comparable to containers but without many of their restrictions in GUI use cases (this topic is focused on desktop use cases, not server, infra, and such). By default, SELinux does not enforce much within user accounts but only around them. But in graphical desktop...
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Nothing will make your system magically more secure, but SELinux is of great help when properly set up (as is in the case of Fedora).
Flatpak using either apparmor or selinux
neither, it uses bubblewrap, snap is the one that uses apparmor