Aspartame is also linked in some studies to weight gain, GI disorders, mental health issues and more:

According to some studies, aspartame and other artificial sweeteners can lead to weight gain instead of weight loss 12. Aspartame has been linked to increased appetite, diabetes, metabolic derangement and obesity-related diseases 2.

One study showed that aspartame causes greater weight gain than a diet with the same calorie intake but no aspartame 1. Another study found that even acceptable daily intakes of aspartame might make you hungrier and lead to weight gain 3.

…some research suggests an association between aspartame intake and metabolic damage to the central nervous system (CNS), such as changes in enzyme and neurotransmitter activities 2. Aspartame acts as a chemical stressor by elevating plasma cortisol levels and causing the production of excess free radicals. High cortisol levels and excess free radicals may increase the brain’s vulnerability to oxidative stress which may have adverse effects on neurobehavioral health 3.

There is also some evidence that high-aspartame consumption may lead to weaker spatial orientation, irritability, depression, and other neurobehavioral conditions 14. However, these studies are limited in scope and further research is needed to determine the long-term effects of aspartame on human health.

Worth researching more, especially if you eat/drink anything with this stuff - and it’s in a lot of food products.

  • Ocularias@lemmy.world
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    1 year ago

    But this line of logic ultimately also ends at “how much aspartame do you need to ingest before it’s bad for you?” A lot of these things end in “you need to consume an unreasonable amount for it to affect you negatively”.

    • YellowtoOrange@lemmy.worldOP
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      1 year ago

      If 100mg causes cancer in 80% of test cases in one year, then it will be very difficult to study how 1mg will affect a group of people, as at lower doses, interactions may become more important.

      If you have a shit diet, don’t exercise, then a smaller dose of aspartame may be more potent- the effect may be additive. It would be too difficult to exclude confounding factors in such a study.

      But luckily no one has the trio of a shit diet, drinks soda and doesn’t exercise :/

      I’m an MD and don’t touch the stuff.

    • YellowtoOrange@lemmy.worldOP
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      1 year ago

      If 100mg causes cancer in 80% of test cases in one year, then it will be very difficult to study how 1mg will affect a group of people, as at lower doses, interactions may become more important.

      If you have a shit diet, don’t exercise, then a smaller dose of aspartame may be more potent- the effect may be additive. It would be too difficult to exclude confounding factors in such a study.

      But luckily no one has the trio of a shit diet, drinks soda and doesn’t exercise :/

      I’m an MD and don’t touch the stuff.