This is the way, never liked broccoli until I learned to make it like this. I love adding different seasonings too depending on the flavor profile of the meal - curry and ginger powder for indian dishes, cajun seasoning if you like spicy, or garlic/lemon/italian seasoning.

The pancreas is not really stable enough to be implanted in at all. Other organs you’re imagining like liver, stomach, heart, etc. have a solid lining that can be cut open and stitched back together. The pancreas is more like a cluster of loose cells with veins throughout and held together by a very thin, tissue paper lining. If you try to open it and insert cells, you’re not going to be able to put it back together.

That’s why cells are usually put in the liver, which has a large vein going directly to the pancreas. Close proximity and high blood supply. Implanting in the pancreas will likely never be an option unless you can drastically reduce the volume of cells.

Our lab was working on implanting the stem cells on a porous scaffold in the fat pad of the stomach as an alternative

Unfortunately, that doesn’t necessarily negate the requirement for immunosuppresors or some other kind of immuno protection. If it is Type 1 diabetes, the person originally became diabetic because the immune system saw certain markers on the beta cells (insulin producing cells) as a threat. So, if you recreate the beta cells, there is still a possibility that it will happen again. You are fighting your own immune system. Someone in our lab was studying encapsulation of cells to create a protective barrier around them for this very issue

If the person was Type 2, this might be less of a risk since type 2 can also be due to high insulin resistivity. There are a lot of other factors involved, though, it’s not straightforward

I literally worked in a research lab working on islet cell therapies for diabetes in the US. This has actually been done many times before with cells from cadavers. It has been successful, although most the of the time the person reverts back after a few years

The issues we were trying to solve in the lab were

1. Finding a good place to transplant where the cells will last: Implanting in the hepatic region (liver), which is the most common place to implant, is toxic to the cells over time hence only lasting 3-5 years. The cells need a really good blood supply and the volume you’re transplanting can’t be easily transplanted in the pancreas or kidney capsules (where many successful studies were performed in mice and rats)

2. Being able to consistently make a high volume of stem cells that are fully grown into insulin producing cells: Cadaver cells usually require 3-5 donors for 1 person and require the receiver to be on lifelong immunosuppresors due to the immune response. Depending on the kind of stem cells, the patient may still even need immunosuppresors due to the cell type you’re converting from

All this the say - the article says nothing about where the cells where transplanted, where they came from, or whether the person has Type 1 or Type 2 diabetes. Although it is still a feat, it is likely not the first time it has been done, and we’re still a long ways off from a cure

Dr. Death was about gross negligence in medicine and the failure of the medical system to prevent unqualified doctors from making it through the system. There’s no evidence that this study has anything to do with that

None of those are mammals…

This title really overly praises him for 1) not doing much at all and 2) making changes that should have been made months ago

The bad part is that their healthcare system still has to deal with the rising number of cases, but it’s not like there has been an unexpected spike from anything unusual

For those who dont feel like reading the whole article, here’s why:

“Much of the increase in kidney failure is caused by an ageing population. When age is taken into account, the number of people with kidney failure as a proportion of the population has remained fairly stable over the past decade, according to data from the registry.”

New fear unlocked

Testosterone does increase risk of heart failure so that is certainly part of it.

Women are also more risk-averse. Risky living = high chance of dying https://m.economictimes.com/magazines/panache/men-have-a-shorter-life-expectancy-than-women-thanks-to-their-genes-says-harvard-study/articleshow/99119402.cms

Pretty sure scalloped doesn’t necessarily mean to bake in cream sauce. It refers to the way they are cut - concentric circles or semi circles to look like scallops (the fish). So although they may look like scallops, there’s no fish in the dish at all.

It sounds like if you’re trying all of this and it’s still not working, something about the way you’re selling yourself isn’t working. Have you tried changing your resume to better match different job descriptions? Try having someone give you feedback on the way you interview. Are you coming on too strong? Maybe you dont have enough specific examples in your answers or too many specifics and not enough leadership/direction. I would also use LinkedIn if you’re not already

Really great shows have a broader plot premise and are free to build new storylines and character arcs each season. As YoBuckStopsHere said, some great shows build up and grow overtime - think Breaking Bad, Parks and Rec. Both shows start off slower, focus on character building in the earlier seasons. Then they become plot focused later on.

Other shows have the flexibility to create new story arcs so each season almost stands on its own but they still stay within the larger overarching premise, example - The Great, Game of thrones (although they really gave up at the end)

I think good shows have a plan for how to get to the end and mediocre shows do as OP described - have a beginning and end planned and not much in the middle. I don’t think all shows are stuck in Act 2, but it does say something that the ones that aren’t stuck there stand out that much more