But for real, don’t mix the two. It’s a great way to end up dead or seriously injured. I had a friend who passed out from the combo in front of a space heater and had burns on his shin that exposed bone.
Also, there’s basically a hard limit on how high you can get with benzos. After a certain point you’re just throwing away money.
Also also, snorting Vyvanse is wasting money. It has to go through stomach acid to work, so it has to drip out of your sinuses first.
Yeah, people are dumb. One of the reasons it’s prescribed is because it’s harder to abuse. According to my psychiatrist when it came out, it’s bonded to a lipid that has to be stripped off by stomach acid to work.
No matter how many times I told my friends they were wasting time and money, they swore it got them higher.
The lysine is cleaved from the prodrug in the bloodstream to release d-amph, not in the stomach. While I haven’t tried it (and wouldn’t recommend it), you should be able to get high from insufflation just fine, but the release curve will be much slower than if you were railing pure speed.
Your friends weren’t talking out of their asses completely. Your psychiatrist isn’t talking out of their ass either, but they’re conflating the mechanism of action that Vyvanse uses with a mechanism used by many other prodrugs, which is first-pass metabolism.
You’re thinking of Strattera (which is worse for adhd than stimulants). Basically every other adhd medication is a stimulant and while they can be formulated in ways that are better for medication than fun it’s usually by making them release slowly and consistently resulting in a milder effect for a longer time. That said, doing that was what perdue pharma said made oxycontin not addictive.
Ah yes Strattera. All it gave me were rancid farts like no other stench I could describe. And the stench clung to me & all around me 24/7 even between farts. No ADD/ADHD benefits whatsoever. Just butt stench.
Yeah strattera is trash. Shit made me feel weird. I had to stop taking it after a week because, aside from the depersonalization and body load, it also.made my heart feel like it was going to self destruct
Yeah I slept through a family vacation as a kid. And it should be noted that we both had adverse reactions. While I’d normally recommend people start with a stimulant, they’ve become really hard to consistently get lately to the point that I’m recommending my wife start with it.
I’m not supporting snorting Vyvanse, but that’s not how it works.
Lisdexamfetamine is an inactive prodrug that is converted in the body to dextroamphetamine, a pharmacologically active compound that is responsible for the drug’s activity.[113] After oral ingestion, lisdexamfetamine is broken down by enzymes in red blood cells to form L-lysine, a naturally occurring essential amino acid, and dextroamphetamine.[6] The half-life of this conversion is roughly 1 hour. The conversion of lisdexamfetamine to dextroamphetamine is not affected by gastrointestinal pH and is unlikely to be affected by alterations in normal gastrointestinal transit times.
Enzymes in your blood convert it to dextroamphetamine, has nothing to do with stomach acid.
What about weed + caffeine?
Alcohol + nicotine?
LSD + MDMA?
Psilocybin + nitrous?
There are a lot of combinations that are extremely safe in regular doses. https://wiki.tripsit.me/wiki/Drug_combinations
But for real, don’t mix the two. It’s a great way to end up dead or seriously injured. I had a friend who passed out from the combo in front of a space heater and had burns on his shin that exposed bone.
Also, there’s basically a hard limit on how high you can get with benzos. After a certain point you’re just throwing away money.
Also also, snorting Vyvanse is wasting money. It has to go through stomach acid to work, so it has to drip out of your sinuses first.
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I never snorted it and I didn’t look for it for fun but if I was out of crystal meth it made me feel better and pretty good.
I’m in recovery now thankfully, don’t do meth kids. Unless you like turning all your bad feelings into good feelings.
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Yeah, people are dumb. One of the reasons it’s prescribed is because it’s harder to abuse. According to my psychiatrist when it came out, it’s bonded to a lipid that has to be stripped off by stomach acid to work.
No matter how many times I told my friends they were wasting time and money, they swore it got them higher.
It’s bonded to an amino acid, lysine.
The lysine is cleaved from the prodrug in the bloodstream to release d-amph, not in the stomach. While I haven’t tried it (and wouldn’t recommend it), you should be able to get high from insufflation just fine, but the release curve will be much slower than if you were railing pure speed.
Your friends weren’t talking out of their asses completely. Your psychiatrist isn’t talking out of their ass either, but they’re conflating the mechanism of action that Vyvanse uses with a mechanism used by many other prodrugs, which is first-pass metabolism.
It has been nearly 20 years since I had the convo with my doc, so I definitely could be misremembering parts of it.
You’re thinking of Strattera (which is worse for adhd than stimulants). Basically every other adhd medication is a stimulant and while they can be formulated in ways that are better for medication than fun it’s usually by making them release slowly and consistently resulting in a milder effect for a longer time. That said, doing that was what perdue pharma said made oxycontin not addictive.
Ah yes Strattera. All it gave me were rancid farts like no other stench I could describe. And the stench clung to me & all around me 24/7 even between farts. No ADD/ADHD benefits whatsoever. Just butt stench.
Yeah strattera is trash. Shit made me feel weird. I had to stop taking it after a week because, aside from the depersonalization and body load, it also.made my heart feel like it was going to self destruct
Yeah I slept through a family vacation as a kid. And it should be noted that we both had adverse reactions. While I’d normally recommend people start with a stimulant, they’ve become really hard to consistently get lately to the point that I’m recommending my wife start with it.
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Why, because street users would fuck up titration and kill themselves‽ That shit is the least I’ve ever minded hives.
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I’m not supporting snorting Vyvanse, but that’s not how it works.
Enzymes in your blood convert it to dextroamphetamine, has nothing to do with stomach acid.
https://en.wikipedia.org/wiki/Lisdexamfetamine
It’s okay if you do it responsibly (no mixing is responsible)
What about weed + caffeine?
Alcohol + nicotine?
LSD + MDMA?
Psilocybin + nitrous?
There are a lot of combinations that are extremely safe in regular doses.
https://wiki.tripsit.me/wiki/Drug_combinations
Caffeine and weed in combination are tragically underrated.
In the oop alcohol and benzos were mentioned, so I was referring to that. Apologies if the language was insufficiently specific.
Oh I see, sorry then. Yeah those two are no good together^^